Pioneering Polyclonal Antibodies
Quotient is a Hyperimmune Globulin human antibody company focused on developing novel products for widespread conditions affecting millions of patients.
Quotient's extensive knowledge and insights have enabled the development, generation, and collection of custom blends of powerful human antibodies with activity in specific disease indications. This capability is rooted in Quotient's ability to identify and select specific donors, immunize them to produce large quantities of desirable antibodies, and then separate and blend these antibodies for specific end uses. This process has led Quotient to develop its current, potentially breakthrough technology platform, trade secrets, and proprietary know-how.
The Human Immune Response is Polyclonal
The Quotient Advantage
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Human Physiology is Polyclonal: A correct immunological response in the body produces a diverse blend of specific antibodies with varied capabilities (polyclonal), rather than just one (monoclonal). This holds true even when confronting a single disease state, as many disease indications are linked to multiple disease pathways.
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Unparalleled safety: Human polyclonal antibodies are widely recognized and accepted by the FDA as safe for human use. This significantly reduces the need for multiple costly and time-consuming safety trials, dramatically decreasing the time and cost to market for Quotient's products.
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Antibody separation without degradation: Quotient possesses a proprietary method for specifically isolating the key “active ingredients” of polyvalent human antibody from blood plasma. This method limits the degradation associated with the fractionation process commonly used today, resulting in a substantially greater active product yield and efficacy, as the refined antibody itself exhibits a greater therapeutic effect.
Unparalleled Safety Profile
Natural human antibodies have been given safely and effectively for more than 50 years. These antibodies are approved through a different regulatory pathway than conventional small molecule and manufactured biologic drugs.
The safety profile of human antibody is unprecedented, with millions of doses given safely each year. Human antibody is known to be safe, by both the FDA and other regulatory bodies worldwide.